Depression is a hard time to go through, and the medication can be of great help to regain the taste for life. Good management of adverse effects of antidepressants is possible, so do not be discouraged when they occur. Medication management to overcome depression is adapted to the patient’s emotional profile on the incorporation of various stressful events. The duration of treatment depends on the severity of the depression. It is important to take your medication as prescribed (dosage, duration) and to notify about your side effects. Moreover, medical follow-ups must be carried out periodically for better recovery.